Serenoa repens
articlemostwanted - Native to the
southeastern United States, saw palmetto is a low-growing palm with
distinctive fan-shaped leaves. Vast, unbroken tracts of saw palmetto
once covered hundreds of miles of coastal land in Florida, Georgia, and
other parts of this region. The density of the plants, coupled with the
sawlike edges of the leaf stalks, made the tracts almost impassable. The
dark purple fruits of saw palmetto—about the size and shape of
olives—were an indispensable dietary staple among Native American tribes
for perhaps as much as 12,000 years before Europeans set foot in this
part of North America. When settlers arrived, they added saw palmetto to
their diet and fed the fruits to their livestock. They also observed
native tribes using saw palmetto, particularly as a remedy for urinary
tract complaints. By the late 1800s, the plant had found its way into
conventional medicine in the U.S. Interest in saw palmetto waned for a
time, but since the 1990s it has been the herb of choice among herbal
practitioners for prostate problems.
Therapeutic Uses
Benign prostatic hyperplasia (BPH)
Saw palmetto’s blue-black, single-seeded berries are
used to make the premier herbal medicine for treating prostate problems.
Extracts of the berries act to inhibit an enzyme, 5-alpha-reductase,
that stops the formation of a potent, prostate growth–enhancing form of
testosterone. Saw palmetto also may have effects on estrogen,
progesterone, and testosterone and their receptors, which are other
mechanisms for slowing the growth of the prostate. All of these effects
translate into easing the symptoms of BPH by enhancing urinary flow
rates, reducing pain with urination, and decreasing nighttime urination.
In most clinical studies, saw palmetto, used as a standardized extract
of 320 mg daily, relieves BPH symptoms as effectively as the
pharmaceutical finasteride; however, finasteride more effectively
decreases the size of the prostate. Whereas finasteride decreases
testosterone levels in the blood, saw palmetto does not seem to affect
blood test results for testosterone, other sex hormones, or
prostate-specific antigen (PSA, a marker for prostate cancer and BPH).
Much research has been done on saw palmetto, and the
research has undergone rigorous analysis in which researchers compiled
results from many studies. The results have been mixed, probably due to
flaws in research models, a range in the type of extracts used, and the
length of time supplements were taken.
How to Use
Extract: Studies have used a specific
extract, standardized at 80 to 90 percent fatty acids and sterols—the
compounds most effective for BPH symptoms—and dosed at 160 mg, twice
daily.
Tincture: 1 to 2 ml, 3 times a day.
Capsules: Follow manufacturer’s guidelines.
Precautions
Saw palmetto can cause mild stomach upset,
constipation, diarrhea, headache, high blood pressure, and itching.
Rarely, saw palmetto can cause impotence or decreased sex drive. Due to
its possible hormonal effects, saw palmetto is not recommended for
people on hormone therapy or for pregnant women. However, women are
unlikely to take this herb anyway.
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